“The phosphoproteomic work of the National Resource team was instrumental in our mapping of an intricate signaling pathway by which mitochondrial dysfunction triggers peri-mitochondrial actin polymerization (PMC9078333).  This work was instrumental in the continued progress of our R35-supported research, and the National Resource team readily supplied a letter of support for our successful renewal in 2022. We now routinely use the resource for proteomics projects large and small. Every time, the facility is highly responsive, delivers results quickly, and is available for follow-up.”

• Henry Higgs, PhD – Dartmouth College
• Service Requests: 8
• Grants Supported: R35GM122545
• Outcomes: Curr Biol (2022) PMC9078333

“Services through the National Resource have had tremendous impact for my lab and eight other labs at the University of Hawaii Manoa, where we have no resources for proteomics. Also, numerous undergraduate students, faculty, and staff from our campus have participated in on-site and virtual education and outreach opportunities provided by the National Resource – opportunities that are particularly impactful for our campus that is an Asian American and Native American Pacific Islander-serving Institution (AANAPISI) and Alaska Native-serving and Native Hawaiian-serving Institution (ANNH).”

• Peter Hoffmann, PhD – University of Hawaii Manoa
• Service Requests: 5
• Grants Supported: R01AI147496, P20GM103466
• Outcomes: JBC (2022) PMC8861121; Mol Biosci (2023) PMC10812114

“The proteomics services provided by the IDeA National Resource for Quantitative Proteomics are exceptional and provided at a fraction of the cost of anyone else. In particular, their bioinformatics group has been instrumental for our ongoing studies evaluating epigenomic drivers of cancer. We routinely use this National Resource to support our NIH-funded work that has resulted in numerous high impact studies that advance the field. I look forward to working with Dr. Tackett and his team in the future and recommend him to all my colleagues with high regard.”

• Greg Wang, PhD – Duke University
• Service Requests: 9
• Grants Supported: R01CA268519, R01CA271603
• Outcomes: Nature (2023) PMC11000523; Oncogene (2022) PMC9189076; Cell Chem Biol (2022) PMC8882712; Nature (2022) PMC8647409; Nucleic Acids Res (2021) PMC8136773

“Participation in the workshop greatly expanded my understanding of the capabilities of modern proteomics.  In addition, it helped me to fully appreciate the superb assets available to investigators by working with the IDeA National Resource for Quantitative Proteomics. As a result of attending this workshop I have considerably expanded my utilization of proteomic methods in my research and have untaken a series of experiments to assess changes in protein expression and cell signaling as a result of specific genetic changes.”

• Roy Jensen, MD – Director, Univ of Kansas Cancer Center
• 2024 Workshop Attendee

“This symposium has had a great impact on my role as Core Manager.  Our Core just acquired an Exploris 480 system, and this symposium provided me with a ton of information regarding the use and upkeep of a system like this. The National Resource has remained an invaluable resource providing maintenance tips, protocols for sample preparation and data collection, as well as insight into data analysis and reporting. I hope to attend this symposium again and continue to foster this productive collaboration.”

• Eric Schultz, PhD – Mass Spec. Core Manager, Univ of Montana
• 2024 Symposium Attendee

“The internship has helped me directly and indirectly during graduate school. I used the preliminary data from the internship to successfully acquire a NRSA F31 grant this spring which activates June 2024. Talking to all the mentors and PIs at the IDeA proteomics center also gave me a better sense of what type of careers I’d be interested in pursuing once I earn a PhD. Thank you all again for providing this opportunity. It was a privilege meeting you all.”

• Pearson McIntire – Graduate Student, University of Nevada, Reno
• 2023 Intern

“I visited the National Resource for a week of training on sample preparation and mass spectrometry data collection. The training was in preparation of opening up new MS and proteomics services at the Geisel School of Medicine at Dartmouth. I was able to prepare and run samples on the same type of MS system at the National Resource that I would be using at Dartmouth. The National Resource team was knowledgeable and helpful. I came away with protocols and confidence that I could reproduce what I had learned. The National Resource team visited Dartmouth a few months later to give a traveling workshop on the fundamentals of proteomics which was well-received and sparked even more interest on our campus towards using global proteomics as a viable tool in research.”

• Noor Taher, PhD – Staff Scientist, Molecular Tools Core, Dartmouth
• 2023 Trainee