Mission
The goals of the IDeA National Resource for Quantitative Proteomics are to provide unmatched and most cost-effective access to state-of-the-art quantitative proteomics platforms and education, outreach, and training opportunities that will increase the capacity of NIH-funded investigators, and others in academic laboratories across the United States, to perform cutting-edge biomedical research. By pursuing our goals, we will support the biomedical research mission of NIH for both fundamental and translational research focused on human diseases including cancer.
Objectives
We aim to achieve our mission by pursuing three main objectives:
- Provide state-of-the-art proteomics services to a nation-wide userbase.
- Provide educational opportunities for quantitative proteomics to a nation-wide userbase.
- Provide outreach and training for quantitative proteomics to a nation-wide userbase.
Brief History
During the past seven years, the IDeA National Resource for Quantitative Proteomics has grown from a regional operation to a fully established National Resource serving a substantial userbase of biomedical researchers across all fifty states plus Puerto Rico. Directed by Alan Tackett, PhD, the IDeA National Resource for Quantitative Proteomics was launched at the University of Arkansas for Medical Sciences (UAMS) in 2017 using supplemental funding from the NIGMS Institutional Development Award (IDeA) Program, a program that supports research in 23 states and Puerto Rico (i.e., IDeA Network) that have historically received lower levels of NIH funding. The creation of the IDeA National Resource for Quantitative Proteomics provided a framework for accessing cutting-edge proteomics platforms and skilled staff for the nation-wide IDeA Network. From 2017-2020, we achieved economy of scale to serve the IDeA Network for service, education, outreach, and training. With our resource achieving economy of scale and having bandwidth for growth, we secured support as a NIGMS R24 National Resource (R24GM137786; 2020-2025) to expand our operation beyond the IDeA Network to biomedical researchers across the entire United States. The first four years of the current R24 funding cycle have shown tremendous growth with service to every state in the United States plus Puerto Rico – including serving 1,426 users, analyzing 28,945 samples, enabling 115 publications, and supporting 482 NIH grants totaling $180,788,790 direct costs. We have provided 485 education, internship, and training opportunities to faculty, students, postdoctoral researchers, and staff; and provided 157 outreach vouchers to investigators for fully subsidized proteomics services. Our 10-fold growth in sample volume has come with decreasing recharge rates, demonstrating we achieved economy of scale and provide the most cost-effective access to quantitative proteomics services. We believe our accomplishments are unrivaled for proteomics service providers and position us for expansion of service, education, outreach, and training opportunities in the renewal.