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Instrumentation

Obritrap Exploris 480 Mass Spectrometers

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The Orbitrap Exploris 480 mass spectrometer (Thermo Scientific) combines a quadrupole mass filter with a high-field Orbitrap mass analyzer and high-capacity ion transfer capability to optimize scan rate, sensitivity, and resolution.

Improvements over earlier generation instruments in this class include significantly enhanced instrument sensitivity largely due to improved ion transfer capabilities, improved instrument robustness and serviceability, and compatibility with next-generation ion sources such as the FAIMS Pro (high field asymmetric ion mobility spectrometry) ion source.

The facility is equipped with two of these instruments, which are used primarily for data-independent acquisition (DIA).